ISSN: 2167-7948
+44 1300 500008
Zeynep Zengin
Turkey
Research Article
The Effect of Hyperthyroidism on Bone Mineral Density in Premenopausal Women
Author(s): Zeynep Zengin and Ayse Cikim Sertkaya
Zeynep Zengin and Ayse Cikim Sertkaya
Background: The effects of subclinical hyperthyroidism and clinical hyperthyroidism on bone metabolism in premenopausal women are contradictory.
Methods: Sixteen hyperthyroid (31.3±9.5 yrs), 23 subclinical hyperthyroid (33.7±7.3 yrs) and 20 healthy (31.7±8.1 yrs) premenopausal women were evaluated. Bone mineral density (BMD) was assessed by dual energy X-ray absorptiometry (DXA). Osteocalcin, total alkaline phosphatase (tALP), homocysteine, β-2 microglobulin, hsCRP and deoxypyridinoline (DPD) concentrations were assessed. Demographic and anthropometrical parameters; and osteoporotic risk factors were evaluated.
Results: Serum calcium, tALP, osteocalcin, β-2 microglobulin and DPD were significantly different in hyperthyroid group. However there was no difference for any of the study pa.. View More»
DOI:
10.4172/2167-7948.1000104