Anatomy & Physiology: Current Research
Open Access

Zoltan Borbas

Publications

• Research Article
  Molecular Investigation into the Human Atrioventricular Node in Heart Failure
  Author(s): Halina Dobrzynski, Andrew Atkinson, Zoltan Borbas, Christina M Ambrosi and Igor R Efimov Halina Dobrzynski, Andrew Atkinson, Zoltan Borbas, Christina M Ambrosi and Igor R Efimov
  
  The atrioventricular node (AVN), the molecular basis has been studied in animal models; however, the human AVN remains poorly explored at the molecular level in heart failure patients. We studied ex vivo donor human hearts rejected for transplantation (n=6) and end-stage failing hearts with cardiomyopathy of various etiologies (n=6). Microdissection and quantitative PCR (qPCR) were used to anatomically map mRNA expression in both failing and non-failing hearts from tissue sections through the AVN, atrial and ventricular muscle. In the failing ventricle significant (P.. View More»
  DOI: 10.4172/2161-0940.1000164

  Abstract PDF

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