ISSN: 0974-276X
Zoran Minic
3737 Wascana Parkway, SK S4S0A2
Canada
Review Article
Proteomic Studies of the Effects of Different Stress Conditions on Central
Carbon Metabolism in Microorganisms
Author(s): Zoran MinicZoran Minic
The ability of cells to respond rapidly to fluctuations in environmental conditions such as thermal stress, pH, hypoxia, exposure to radiation, chemicals and a number of other factors is important for competitive fitness, adaptation and cell survival. To understand the dynamics of the complex metabolic pathways involved, various approaches including genomics, transcriptomics, proteomics, metabolomics, kinetics and biochemical information are appropriate. Proteomics is useful for evaluating the expression profiles of proteins, their post-translational modification and interactions between molecules. This review summarizes recent proteomics data examining the effects of different stress conditions on central carbon metabolism (CCM) in microorganisms. Data, primarily on enzymes involved in glycolysis, the tricarboxylic acid cycle and pentose phosphate pathways, were extracted from variou.. View More»
DOI:
10.4172/jpb.1000355