ISSN: 2329-6917
+44 1300 500008
Clinical Pathology Department, Al-Hussein University Hospital, Egypt
Dr. Abdelraoof A Abo-Nar is an Associate professor in Clinical Pathology Department, Al-Hussein University Hospital, Egypt. Currently, Dr. Abdelraoof A Abo-Nar is the author/editors/reviewer in several international journals. He published 10 articles in many journals and the articles are informative and got good citations.
Research Article
Role of Interleukin17F (IL17F) Gene Polymorphism in Susceptibility to Acute Myeloid Leukemia
Author(s): Karima A Mahfouz, Abdelraoof A Abo-Nar and Sara M Bendary*
Abstract: Th17 cells (subset of CD4+ cells) are characterized by interleukin (IL)-17A and IL-17F production, which share strong homology, and surface expression of the IL-23 receptor (IL-23R). They have been implicated in the pathogenesis of inflammatory, autoimmune diseases and in many different types of human tumors, including lymphoma and myeloma.
Objectives: The aim of this study was to determine the association between the polymorphic features located within the IL-17A, IL-17F and IL-23R genes and susceptibility to or association with AML and the relationship between these polymorphic variants and the plasma IL-17 levels in all studied groups.
Subjects and Methods: 82 individual of Egyptian population including 27 AML patients, 40 individual who are relatives of those patients and 15 apparently healthy controls. All.. View More»
DOI:
10.35248/2329-6917.19.7.252