Journal of Cell Science & Therapy

Journal of Cell Science & Therapy
Open Access

ISSN: 2157-7013

+44 1300 500008

Abdelwahed Wayne

Department of Cell Biology, Yale University, New Haven, USA

Biography

Dr. Abdelwahed Wayne is a distinguished researcher in the Department of Cell Biology at Yale University in New Haven, USA. His work focuses on molecular cytotechnology, a field that integrates genetic analysis with cellular diagnostics to enhance our understanding of cellular functions and disease mechanisms. This multidisciplinary approach combines cytotechnology with molecular biology techniques, providing deeper insights into cell behavior, genetic alterations, and disease processes. "Molecular Cytotechnology: Integrating Genetic and Cellular Insights," Dr. Wayne explores the fusion of cytotechnology and molecular biology. He discusses how traditional cytotechnology, which focuses on the microscopic examination of cells to diagnose diseases like cancer, is enhanced by molecular biology techniques such as Polymerase Chain Reaction (PCR), In Situ Hybridization (ISH), and Next-Generation Sequencing (NGS).  By identifying specific genetic mutations, chromosomal abnormalities, and gene expression profiles, techniques like Fluorescence In Situ Hybridization (FISH) and Chromogenic In Situ Hybridization (CISH) detect genetic abnormalities in cancer cells, facilitating targeted therapies. Additionally, his work emphasizes the importance of genetic testing in detecting disorders and predispositions by analyzing genetic material from cells, aiding in the identification of mutations associated with diseases such as cystic fibrosis, muscular dystrophy, and inherited cancers.

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