Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Department of Medicine, Azerbaijan Medical University, Baku, Azerbaijan
Research
The Effects of Intraoperative High-Dose Ketamine on Postoperative Pain in Patients Undergoing Lumbar Surgery: A Prospective Study
Author(s): Abdullah Al-Murad*
Background: Postoperative pain management is a challenging aspect of patient care. To enhance traditional analgesics for postoperative pain, ketamine has been utilized as an adjuvant. However, the most appropriate dosage of ketamine has yet to be determined. This study sought to investigate the effects of administering a high dose of ketamine during surgery on postoperative pain experienced by patients undergoing lumbar surgery.
Methods: A prospective study involving 800 patients undergoing lumbar surgery was conducted. Patients were randomly allocated into two groups: the ketamine group (n=400) received an intravenous dose of 1 mg/kg of ketamine after anesthesia inductions, followed by a continuous infusion of 0.20 mg/kg/hour throughout surgery, while the control group (n=400) received normal saline. Pain intensity was assessed usin.. View More»
DOI:
10.35248/2155-6148.23.14.1103