Journal of Proteomics & Bioinformatics
Open Access

Schiller International University, Heidelberg Campus, Zollhofgarten 1, 69115 Heidelberg, Germany

Publications

• Research Article   
  GraphBreak: Tool for Network Community Based Regulatory Medicine, Gene Co-expression, Linkage Disequilibrium Analysis, Functional Annotation and More
  Author(s): Abhishek Narain Singh*
  
  Graph network science is becoming increasingly popular, notably in big-data perspective where understanding individual entities for individual functional roles is complex and time consuming. It is likely when a set of genes are regulated by a set of genetic variants, the genes set is recruited for a common or related functional purpose. Grouping and extracting communities from network of associations becomes critical to understand system complexity, thus prioritizing genes for disease and functional associations. Workload is reduced when studying entities one at a time. For this, we present GraphBreak, a suite of tools for community detection application, such as for gene coexpression, protein interaction, regulation network, etc. Although developed for use case of eQTLs regulatory genomic net-work community, study-results shown with our analysis with sample eQTL .. View More»
  DOI: 10.35248/0974-276X. 23.16.625

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