Pharmaceutical Analytical Chemistry: Open Access
Open Access

The University of Jordan, Jordan

Biography

Abu Fara D. has completed his PhD from McGill University, Canada. He is associate professor at the Chemical Engineering Dept., University of Jordan, Jordan. His current research interest is in the field of the application of natural polymers in the pharmaceutical industry.

Publications

• Short Communication   
  Novel direct compression polymeric excipients from chitin and its derivatives for pharmaceutical applications
  Author(s): Abu Fara D
  
  Chitin and its derivative were investigated as novel direct compression (DC) excipients for immediate and controlled release applications. In the former, roller compaction technology was employed in a specific manner to convert the low bulk density, poor flowability and low compactibility of chitin powder into a DC excipient. In the latter, a combination of low molecular weight chitosan (LCS) with xanthan gum was found to provide the basis for controlled release preparations. The novel excipients were characterized using XRPD and FTIR tests. Compressibility and compactibility of the powders were examined thereafter using flow indices, Heckel and Kawakita analysis, and force-displacement curve. The novel excipients showed improvement in powder flow, high resistance to compression force, and high extent of plastic deformation. This work further elaborated on the role of LCS in the enhan.. View More»
  DOI: 10.35248/2471-2698.20.5.151

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