Journal of Women's Health Care
Open Access

Department of Obstetrics and Gynaecology, Federal Medical Centre, Makurdi, Benue State, Nigeria

Publications

• Research   
  Efficacy of Letrozole in Comparison with Clomiphene Citrate for Induction of Ovulation in Polycystic Ovary Syndrome with Infertility
  Author(s): Agulebe Chiahemba Joseph*, Nombur Isaac Lahaga, Abu Paulinus Oshiotse and Omoregie Irowa
  
  Background: Polycystic Ovary Syndrome (PCOS) is a complex metabolic disorder affecting 5 to 10% of women of reproductive age group, with key features including; menstrual cycle disturbance, obesity, hyperandrogenism and the commonest cause of an ovulatory infertility. An effective, simple and safe treatment of PCOS is an important public health initiative with the recent introduction of letrozole as against the traditional use of Clomiphene citrate for ovulation induction in affected patients. Objective: The objective of this study was to compare the efficacy and safety of letrozole in the induction of ovulation in infertile an ovulatory PCOS patients in comparison with clomiphene citrate. Methodology: One hundred and forty-two infertile patients aged 18 to 40 years that met the inclusion criteria for infertile an ovulatory PCOS were recruited and randomized by computer-base.. View More»
  DOI: 10.35248/2167-0420.23.12.695

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