Andrology-Open Access
Open Access

Department of Biomedical Engineering, School of Engineering, Brown University, 182 Hope Street, Providence, RI-02912, USA

Biography

Adam Spooner is an Associate Researcher in the Department of Biomedical Engineering at Brown University's School of Engineering, located at 182 Hope Street, Providence, RI 02912, USA. His research focuses on diagnostics, microfluidics, drug delivery, and automated liquid handling systems.

Publications

• Research Article   
  Understanding Sample Preparation Workflow: Semi-Automated Preparation of Serum Testosterone for Detection Using LC-MS/MS
  Author(s): Ramisa Fariha, Collin Hill, Mohannad Jabrah, Adam Spooner and Anubhav Tripathi*
  
  High-performance liquid chromatography-tandem mass spectrometry has been pivotal to recent clinical advancements in the detection and monitoring of the progression of different metabolic disorders. Such systems have been used to routinely monitor serum testosterone levels in patients, to both mitigate side effects of different medications, as well as diagnose androgen-associated disorders. The present study develops and validates an LC-MS/MS-based assay for the detection of total serum testosterone from only (100 μL) of sample volume. To increase the high throughput capability of the developed diagnostic kit for clinical use on patient samples, the proposed method was streamlined via semi-automation on a JANUS® G3 Workstation liquid handler. The proposed diagnostic kit showcased high detection precision (CV<5%) as well as sample accuracy (93%-108%), withi.. View More»
  DOI: 10.35248/2167-0250.24.13.329

  Abstract HTML PDF

Other relevant publications from this author

• https://tripathi.engin.brown.edu/copy-of-publications?utm_source=chatgpt.com

  https://tripathi.engin.brown.edu/copy-of-publications?utm_source=chatgpt.com

  https://scholar.google.com/citations?user=G7eT_rcAAAAJ&utm_source=chatgpt.com

  https://scholar.google.com/citations?user=G7eT_rcAAAAJ&utm_source=chatgpt.com