Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Department of Biotechnology, University of Malakand, Chakdara, Pakistan

Publications

• Review Article   
  In silco Prediction of Target Genes for Up-Regulated MicroRNAs in Male Infertile Patients
  Author(s): Mushtaq Ahmad* and Aftab Ali Shah
  
  MicroRNAs are small molecules that control expression post transcriptionally. Due to diversity in microRNAs and difficulty in experimental identification of target genes, the specific function of most microRNAs are not known. It is necessary to find their target mRNAs. Computational target prediction helps MiRNA-mRNA interactions for experimental studies. Infertility is an important health related problem. Approximately 10-15% of couples face infertility problem worldwide. About 50% of infertility issues are attributable to male factors. A large number of infertility cases are idiopathic, since their molecular mechanism is unknown. MicroRNAs are differentially expressed in male patients with complications in fertility. They are involved in regulating various reproductive processes such as embryogenesis and spermatogenesis. The current study was carried out to find out the importan.. View More»
  

  Abstract PDF