ISSN: 2155-9554
+44 1478 350008
Department of Dermatology, Venereology and Andrology, Ain Shams University, Egypt
Ahmed Abdelfattah Afify belongs to the Department of Dermatology, Venereology and Andrology, Ain Shams University, Cairo, Egypt. Dr. has a special interest in Dermatology, Skin, Psoriasis; Repigmentation.
Research Article
Evaluation of Serum CXCL10 in Relation to Minigraft Test in Detecting
Stability of Vitiligo
Author(s): Marwa Abdallah, Ahmed Abdelfattah Afify*, Marwa Kamal Asaad and Reham Mohamed Ahmed Hassan
Objectives: Stability is an essential aspect in the surgical treatment of vitiligo. One or more year stability has been suggested for better surgery outcome. Recently, the chemokine CXCL10 has emerged as a putative serum marker that correlated with disease activity. The aim of the current work was to evaluate the serum level of CXCL10 versus minigrafting in predicting surgical stability in vitiligo.
Methods: Fifteen patients with 6-11 months stable disease (group 1) and fifteen patients with at least 12 months stability (group 2) were subjected to a minigraft test and evaluation of serum level of CXCL10. Repigmentation was evaluated at 3 months.
Results: Serum level of CXCL10 was not different between both groups (p >0.05). Minigraft test was positive in 40.0% in group 1 vs. 86.7% in group 2 (p=0.008). .. View More»