Journal of Plant Biochemistry & Physiology
Open Access

Institute of Systems Biology (INBIOSIS), University Kebangsaan Malaysia, Selangor, Malaysia

Biography

Dr. Ahmed Mediani is a Professor at Universiti Kebangsaan Malaysia, Institute of Systems Biology (INBIOSIS), Malaysia. He had worked on a Metabolomics study for dereplication of selected Algerian plants. His study interests are mainly in Metabolomics, Bioactivity, Antioxidants, DPPH, Antioxidant Activity, Mass Spectrometry, Liquid Chromatography, Metabolite Identification, and Phytochemicals. He had published 62 articles and got 909 citations and good reading responses. He had worked on 4 projects mainly on metabolomics which looks good to read and is well explained it seems to be interesting and informative.

Publications

• Research Article   
  Identification of Antihypertensive Mechanisms ofFicus deltoidea kunstleri; in Spontaneously Hypertensive Rats Using Metabolomics
  Author(s): Harbindar Jeet Singh*, Norasikin Ab Azis, Mohd Saleh Ahmad Kamal, Ahmed Mediani, Renu Agarwal, Zurain Radjeni and Nor Hadiani Ismail
  
  Blood pressure lowering effect of Ficus deltoidea kunstleri (FDK) has been associated with changes in the Renin-Angiotensin-Aldosterone System (RAAS) and endothelial function in Spontaneously Hypertensive Rats (SHR). Whether it also involves other systems is unclear. This study therefore screened for other potential BP lowering mechanisms in FDK-treated SHR based on urine metabolite profile obtained using 1H-NMR spectrometry and multivariate data analysis. Male SHR were administered orally, either 0.5 mL of distilled water (control), or 1000 mg.kg-1 body weight of FDK or 10 mg.kg-1 body weight of losartan once daily for 4 weeks. BP was measured weekly and 24-hr urine was collected using metabolic chambers at the end of the 4th week. Animals were then euthanised and blood was collected for estimation of total anti-oxidant capacity TAC. Kidneys we.. View More»
  DOI: 10.35248/2329-9029.21.9.261

  Abstract HTML PDF