Journal of Clinical Trials
Open Access

Department of Internal Medicine and Nephrology, Fayoum University, Faiyum, Egypt

Publications

• Research Article   
  Detection of Hepatitis C Viral Particles in Renal Tissue in Patients with HCV Associated Nephropathy: A Clinic Pathological Study
  Author(s): Mohamed Hussein Elmahdi*, Ahmed Mohammed Rashed and Alaa Saad Abd Elhamid
  
  Introduction: Patients with Hepatitis C Virus (HCV) develop different types of renal injuries. Membranoproliferative Glomerulonephritis (MPGN) is the most common type occurs in HCV patients who are complicated with small- vessel vasculitis cryoglobulinaemia. The aim of this work is to study the detection of HCV-RNA in the renal tissue using both Polymerase Chain Reaction and In Situ Hybridization (PCR and ISH) Techniques. In addition, we investigate the different patterns of renal affection in association with HCV infection. Methods: The material of this work consisted of 50 native renal biopsies taken from HCV seropositive patients with renal lesions. All cases were collected as paraffin-embedded blocks. All cases were examined using a light microscope and evaluated according to the type of renal tissue as well as assessment.. View More»
  DOI: 10.35248/2167-0870.24.S30.001

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