Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Infection Control Committee, Shimonoseki City Hospital, Koyo-cho, Shimonoseki, Japan
Research Article
Does the Pandemic Influence Antimicrobial Stewardship? A Historical Control Study before and after Severe Acute Respiratory Syndrome Coronavirus-2 Infection Care in a Teaching Hospital
Author(s): Junichi Yoshida*, Kenichiro Shiraishi, Tetsuya Kikuchi, Akiko Mataga, Takako Ueno, Takahiro Noda, Kazuhiro Otani and Masao Tanaka
Background: To see whether the COVID-19 pandemic influenced the 3-year use of parenteral antimicrobials, we attempted a historical control study.
Methods: Materials were the electronic medical record on the use of a total of 33 antimicrobials. We compared Antimicrobial Use Density (AUD, total dose/Defined Daily Dose/patient-day × 100) of Pre-pandemic 1 Year (PreY), the first Pandemic Year (Pan1Y), and the second Pandemic Year (Pan2Y). Our antimicrobial team monitored all in-patients and COVID-19 patients underwent clinical pathways with antivirals.
Results: Results showed that in a total of 20,013 patients (7,534, 6,146, and 6,333 for PreY, Pan1Y, and Pan2Y), sepsis-3 was diagnosed in 152, 132, and 283 patients while Clostridioides difficile toxin tests were positive in 17, 5, and 7 patients, respect.. View More»
DOI:
10.35248/2167-0870.22.S18.001