ISSN: 2167-0870
Department of Gastroenterology, Cukurova University, Adana, Turkey
Dr. Akkiz H is currently working in Department of Gastroenterology, Cukurova University, Adana, Turkey. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his valuable service towards the scientific community with his extensive research work.
Research Article
Erythrocyte Sedimentation Rate and C-Reactive Protein are Markers for Tumor Aggressiveness and Survival in Patients with Hepatocellular Carcinoma
Author(s): Brian Carr*, Akkiz H, Guerra V, Donghia R, Yalçin K, Karaogullarından U, Altıntas E, Ozakyol A, Şimşek H, Balaban HY, Balkan A, Uyanıkoglu A and Ekin N
Introduction: Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are acute phase reactants in
clinical use for monitoring inflammatory diseases for several decades. CRP is also prognostically useful in several
cancers.
Objective: To evaluate the role of ESR as a possible indicator of tumor biology and survival in patients with
hepatocellular carcinoma (HCC).
Methods: A large cohort of HCC patients in Turkey was examined retrospectively for clinical and tumor
characteristics with respect to blood CRP and ESR levels.
Results: Portal vein thrombosis and high Aggressiveness Index were significantly related to elevated CRP or ESR
levels and especially to the combination of elevated CRP and ESR, both in the total cohort and in patients with small
tumors &l.. View More»