Endocrinology & Metabolic Syndrome
Open Access

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Biography

Dr. Akshaya Jayachandran is an Associate professor in the Department of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India and published 8 articles in many journals and the articles are informative and got good citations.

Publications

• Case Report   
  Tumour Induced Osteomalacia-Unique Presentation
  Author(s): Krishna Kumar Chinnadurai* and Akshaya Jayachandran
  
  Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia is a rare paraneoplastic syndrome characterized by severe persistent hypophosphatemia. It occurs due to excess production of phosphatonins, which clinically manifests as severe hypophosphatemia. In our case, a 37-year-old woman presenting with multiple joint pains for last 9 years, progressive weakness of bilateral lower limbs for the last 1 year and past history of long bone fractures was diagnosed with tumor-induced osteomalacia (TIO) although she had normal FGF23 levels. TIO was caused by phosphaturic mesenchymal tumour in right tibia. After surgical resection of the tumour, her symptoms resolved. This is a unique case in that the patient had a normal systemic FGF23 level even with severe manifestations of TIO and also patient had raised parathyroid hormone levels which create a confusion of parathyroid related.. View More»
  DOI: 10.35248/2161-1017.20.9.317

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