Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Molecular Sciences, Imperial College London, London, United Kingdom

Publications

• Research Article   
  A Rapid Urine Sensor for Detection of Sports Anaemia in Ultra-Endurance Athletes
  Author(s): Owen T. Griffiths*, Alan C. Spivey, Gregory Quinlan and Anthony E.G. Cass
  
  Background: Sports anaemia is a condition associated with high levels of haemolysis after intensive exercise such as ultra-endurance rowing competitions. Studies have shown that large or continuous muscle contractions can increase the fragility of Red Blood Cells (RBCs), which can lead to intracapillary mechanical haemolysis. Toxicity from haemolysis is caused by the release of cell free Haemoglobin (cfHb), haem and iron from the lysed RBCs. Early detection of sports anaemia can prevent toxicity by facilitating earlier intervention of preventative treatments. However, there are currently no rapid, low-cost and easy-to-use sensors to detect sports anaemia. Methods: An electrochemical sensor was developed to detect cfHb in urine which is a good biomarker for haemolysis. The sensor utilises low-cost carbon black and screen-printed electrodes. Th.. View More»
  DOI: 10.35248/2736- 6588.24.7.296

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