ISSN: 2329-9495
+44 1478 350008
Department of Hemodynamic, Centro Médico Nacional “20 de Noviembreâ€, ISSSTE, Av. San Lorenzo 502, Col. del Valle, C.P. 03229, México City, Mexico
Alcántara-Meléndez is currently working as Professor at Department of Hemodynamic, research works includes studies on rotational atherectomy in the treatment of high-risk calcified coronary lesions and the applicability of proximal and distal transradial access, coronary circulating mononuclear progenitor cells and soluble biomarkers in the cardiovascular prognosis after coronary angioplasty.
Research Article
Relation of Coronary Artery Lumen with Baseline, Post-angioplasty Coronary Circulating Pro-Inflammatory Cytokines in Patients with Coronary Artery Disease
Author(s): Juan Antonio Suárez-Cuenca*, Vera-Gómez E, Hernández-Patricio A, Gutiérrez-Buendía JA, Domínguez-Pérez GA, Robledo-Nolasco R, Alcántara-Meléndez MA and Mondragón-Terán P
Background: Atherogenic progression in Coronary Artery Disease (CAD) involves a chronic inflammatory process, where local production or release of pro-inflammatory mediators into coronary circulation has a main role. Proinflammatory cytokines IL-6, TNFα and IL1β have been particularly related with the atheroma plaque and CAD severity.
Aim: To explore whether characteristics of the coronary artery affected by atheroma plaque were related with coronary circulating pro-inflammatory cytokines and their modifications after angioplasty.
Methods: Patients with CAD and stable coronary plaque, submitted to coronary angiography and stenting. Coronary artery lumen diameter at the site of the main atherogenic lesion was measured by intravascular ultrasound, whereas IL-6, TNFα and IL1β concentration in cor.. View More»
DOI:
10.35248/2329-9495.19.7.227