ISSN: 2576-1447
+44 1478 350008
Department of Ophthalmology and Ophthalmic Oncology, Jagiellonian University Medical Collegium, Krakow, Poland
Commentary
A Short Note on Metastatic Cancer and Its Resistance
Author(s): Alex Pajno*
Metastatic cancer, characterized by the spread of cancer cells from the primary tumor to distant sites in the body, is a
immense difficulty in oncology. This resistance can develop as insensitivity to chemotherapy, targeted therapies,
immunotherapies, or hormonal treatments, making metastatic cancer extremely difficult to control. Understanding
the mechanisms behind treatment resistance is essential for improving patient outcomes. Metastatic cancer cells use a
range of adaptive strategies to evade the effects of therapeutic interventions. These mechanisms may involve
genetic alterations, such as the development of unexpected mutations or gene amplifications that render cancer
cells less susceptible to treatment. Additionally, cancer cells can activate signaling pathways that elevate their
survival and growth, preventing the intended effects of drugs. The heterogen.. View More»
DOI:
10.35248/2576-1447.23.8.546