ISSN: 2157-7064
+44 1300 500008
Department of Analytical Chemistry, University of California, Los Angeles, USA
Dr. Alexander Dikiy is a researcher in the Department of Analytical Chemistry at the University of California, Los Angeles (UCLA), USA. His work focuses on the formation mechanisms and analytical utility of [M+2NH?]? ions in Liquid Chromatography-Mass Spectrometry (LC-MS). In his recent publication, "The Formation Mechanisms and Analytical Utility of [M+2NH?]? Ions in LC-MS," Dr. Dikiy explores the characteristics, formation mechanisms, and applications of these ions in LC-MS analysis. LONGDOM In this study, Dr. Dikiy discusses how the [M+2NH?]? ion is formed by the addition of two ammonium ions (NH??) to the analyte molecule (M) during the ionization process in mass spectrometry. He examines the role of ammonium salts or buffers in the mobile phase or sample matrix, which can result in the formation of [M+2NH?]? ions through cationization. The research highlights the importance of understanding the formation mechanisms of these ions for compound identification, quantification, and structural elucidation in LC-MS analysis. LONGDOM Dr. Dikiy's research contributes significantly to the field of analytical chemistry by enhancing the understanding of ion formation in LC-MS, thereby improving the accuracy and reliability of mass spectrometric analyses. His work has implications for various applications, including pharmaceuticals, environmental analysis, food safety, and metabolomics, where precise and accurate analytical techniques are essential.
Opinion
The Formation Mechanisms and Analytical Utility of [M+2NH4]+Ions in L C-MS
Author(s): Alexander Dikiy*
DOI:
10.35248/2161-0940.24.15.555