Emergency Medicine: Open Access
Open Access
ISSN: 2165-7548
ISSN: 2165-7548
Department of Neurosurgery, Hamadan University of Medical Sciences, Hamadan, Iran
Research Article
The Effect of Curcumin in the Recovery of Severe Traumatic Brain Injury: A Double-Blind Randomized Controlled Trial
Author(s): Mohammadreza Saatian, Masoumeh Roustaei, Ebrahim Jalili*, Sara Ataei, Ali Poormohammadi, Maryam Farhadian and Ali Abdoli
Background: Traumatic brain injury is one of the most important causes of death in trauma patients among the
different types of trauma worldwide. In this study, the effect of Nano Curcumin on the outcome of severe traumatic
brain injury, which was performed in humans for the first time, was investigated.
Methods: This was a double-blind and paralleled randomized controlled study that was conducted on 128 patients
aged 18 to 70 with severe brain trauma. Patients were randomly assigned to two control groups (Standard care
treatment+placebo) and an intervention group (Standard care treatment+oral Nano Curcumin with the dose of 500
mg every 8 hours for three weeks). Changes in the level of consciousness, cerebral edema, kidney function, liver
enzymes, sodium and potassium electrolytes, and brain function of patients in both group.. View More»
DOI:
10.4172/2165-7548.22.12.251