ISSN: 2684-1630
+44 1300 500008
Department of Ocular Oncology, Tehran University of Medical Sciences, Tehran, Iran
Dr. Ali Haghbin belongs from the Department of Ocular Oncology at Thomas Jefferson University in Philadelphia, PA, USA. He specialises in fields of oncology, Human Oncology, Health, Development biology, life biology. Dr. Ali Haghbin is the author/editors/reviewer in several international journals. He published 10 articles in many journals and the articles are informative and got good citations.
Review
A Mini-Review of Ocular and Periocular Rosai-Dorfman Disease: A Masquerading Pathology with Unknown Etiology
Author(s): Babak Masoomian*, Ali Haghbin and Shahriar Ghodous
Rosai-Dorfman disease (RDD) is a rare sub type of non-Langerhans cell histiocytosis with a predilection for the head and neck that specially involve cervical lymph nodes. Classic histopathologic features include emperipolesis and Immunohistochemical stains are strongly positive for S-100 and CD68 but negative for CD1a in most cases. The exact nature and RDD etiology remains unknown. More than 40% of RDD patients show extra nodal involvements. Ophthalmic manifestations can be detect in 10% of all patients in which, the highest prevalence is related to orbital lesions. In the presence of orbital and intraocular lesions, systemic involvements are more likely to be associated. There is no specific treatment for this disease therefore, treatment modalities should be individualize based on site of involvement and presence or absence of systemic involvement... View More»