ISSN: 1948-5964
+44 1300 500008
Department of Epidemiology, High Institute of Public Health, Alexandria, Egypt
Ali Hasab works at Department of Epidemiology, High Institute of Public Health, Alexandria University, Alexandria, Egypt. His area of research interests includes Infectious diseases, Virology . He /she has authored of many research articles/books in the relevant scope.
Research Article
Non-Randomized Clinical Trial to Interrupt Vertical Hepatitis B Viral Infection
Author(s): Khaled A. Abu Ali*, Ali Hasab, Noha Awad and Yehia Abed
Background: Hepatitis is an inflammation of the liver, can be self-limiting or progress to fibrosis, cirrhosis, or
hepatocellular carcinoma, HB occurs as a result of parenteral contact with infected body fluids, could be vertical
from mother to baby or horizontal.
Aim of the study: To assess the effectiveness of HB vaccine alone versus HBIG combined with HB vaccine in the
interruption of neonatal HB viral infection.
Methods: A Non-randomized clinical trial was conducted, 228 subjects distributed into two groups, the control
group: newborns of mothers with inactive HBV infection were given HBIG and HB vaccine and, the intervention
group: Newborns of mothers with inactive HBV infection were given HB vaccine alone.
Results: showed that the two immunization regimens were effective in.. View More»
DOI:
10.35248/1948-5964.21.s20.003