Journal of Molecular Pathology and Biochemistry
Open Access

Hematology Department, Allied Medical School, TUMS, Enqelab Ave, Tehran, Iran

Biography

Shaban Alizadeh, Professor in Department of Hematology , Allied Medical School, TUMS, Enqelab Ave, Tehran, Islamic Republic of Iran. Expertise in Diagnostic Hematology tests, ELISA, MTT and toxicity assay, Cell culture techniques, Stem cell culture (mesanchymal, hematopoetic , embryonic and iPS), Molecular biology techniques including DNA and RNA purification, PCR, Real time PCR, RT-PCR, DNA electrophoresis, Cloning, miRNA cloning , upreg and downreg.

Publications

• Review Article   
  Study of Serum Thrombospondin-1 Level in Diabetic Patients with Diabetic Foot Ulcer
  Author(s): Alizadeh S*, Beige ZB, Poor Heravi SA, Nejad FS, Shokri MM and Nazar M
  
  Thrombospondins (TSP) are a group of multifunctional secretion proteins that consist of TSP-1 to TSP-5. TSP-1 is the first protein member of this family and a homotrimeric glycoprotein with a multifunctional domain. The aim of this study is to evaluate the level of TSP-1 and its impact on vessels in diabetic patients. In 2016, 90 diabetic patients were selected from Golestan hospital and Emam Khomeini hospital, they were put into three different groups; 30 patients (FBS over 126 mg/dL) without a diabetic foot ulcer (DFU) (group 1), 30 diabetic patients (FBS over 126 mg/dL) with a DFU (group 2), 30 people without diabetes or DFU (group 3). In all patients, Hemoglobin A1c (HbA1c), blood sugar, and TSP-1 tests were performed. Results: The mean amount of TSP-1 in group 1, 2, and 3 was 266.85 ± 88.75 ng/mL, 234.87 ± 129.8 ng/mL, and 1570.4.. View More»
  

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