Poultry, Fisheries & Wildlife Sciences
Open Access

Department of Molecular and Cellular Medicine, College Station, Texas A&M University Health Science Center, TX 77843, USA

Biography

Rice-Ficht received her Bachelor of Science from Auburn University and her doctorate from Vanderbilt University in 1980 investigating mechanisms of viral infection. ISince 1984, Rice-Ficht has been a member of the faculty of the Texas A&M University Health Science Center continuing her interest in tropical disease and vaccine development.  Rice-Ficht has engineered this capsule or particle with the ultimate goal of creating a needle-free “pocket vaccine” delivery system for the delivery of virtually any vaccine. 

Publications

• Research Article   
  Bacillus anthracis Sterne Strain 34f2 Vaccine Antibody Dose Response by Subcutaneous and Oral Administration
  Author(s): Jamie Benn Felix*, Sankar P Chaki, Thomas A Ficht, Allison C Rice-Ficht and Walt Cook
  
  Anthrax (Bacillus anthracis) is a zoonotic disease endemic to environments worldwide. Spores, the dormant form of the bacteria, can survive for decades in nature’s harshest environments and maintain their viability to cause disease. Outbreaks are common in free-ranging livestock and wildlife, thus making anthrax an economically and ecologically important disease. The currently available vaccine to protect livestock is a suspension of B. anthracis Sterne Strain 34F2 spores in saponin (Sterne vaccine). However, it is only available as a subcutaneous injection which is an impractical method of prevention for wildlife. Oral vaccination is the ideal method for free-ranging wildlife, but the Sterne vaccine has never been thoroughly evaluated for oral administration. The current study evaluated the antibody titers induced in mice by subcutaneous or oral vaccination with three different.. View More»
  DOI: 10.35248/2375-446X.19.7.206

  Abstract HTML PDF