Journal of Leukemia
Open Access
ISSN: 2329-6917
+44 1300 500008
ISSN: 2329-6917
+44 1300 500008
Department of Medicine, King Fahad Specialist Hospital-Dammam Eastern Province, Dammam, Saudi Arabia
Review Article
Clinical Burden and Management of Acute Myeloid Leukemia in the Middle East: Is the System Ready for Precision Medicine?
Author(s): Marashi M*, Awidi A, Rustmani AA, Alhuraiji A, Otaibi AA, Mahrezi AA, Alshehri B, Abdulmajeed B, Nasar B, El-hemaidi E, Soliman H, Yaseen HA, Motabi I, Cheikh JE, Alnahedh M, Al-Khabori M, Alzahrani M, Khudair NA, Blooshi SA, Alwesadi T and Al-Shaibani Z
Advances in understanding AML's genetic mechanisms have transformed patient management and prognosis. However, implementing precision medicine in the Middle-East faces significant challenges in clinical practice and healthcare systems. Therefore, a panel of 21 experts from the Middle-East held two meetings to highlight AML burden in the region and the current management practice for intensive chemotherapy-ineligible patients. Views on the challenges and accessibility of molecular profiling and targeted therapy were discussed, alongside clinical pharmacists’ role in addressing these challenges. They highlighted that the current local data underestimate the disease burden; thus, a national and unified registry for AML cases is recommended. Despite the recent improvement in the referral system for leukemic cases, many challenges still exist, including referral delay, access to .. View More»
DOI:
10.35248/2165-7556-24.12.398