Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Biotechnology, BASIS Independent Silicon Valley, San Jose, California, United States

Publications

• Research Article   
  Discovery of Neurocognitive Phenotypes of Autism by Analyzing Functional Connectivity in the Default Mode Network and Dorsolateral Prefrontal Cortex
  Author(s): Amith Vasantha*
  
  Autism spectrum disorder (ASD) is a neurodevelopmental disorder usually presenting as reduced social interaction, lessened verbal communication, and repetitive behavior. Diagnosing autism spectrum disorder is extremely difficult because of its wide variety of symptoms, so it can only be diagnosed through behavioral tests and analysis of developmental history. Resting-state functional magnetic resonance imaging (rs-fMRI) can help researchers discover a neural substrate for autism spectrum disorder to diagnose it earlier. One prominent fMRI database for autism spectrum disorder research is the Autism Brain Imaging Data Exchange, a large-scale collection of anonymized functional MRI scans subdivided by age, gender, handedness, and scores on behavioral assessments. This analysis focused on two brain networks: the Default Mode Network (DMN), which is active when minds wa.. View More»
  DOI: 10.35248/JCCLM.22.5.221

  Abstract HTML PDF