Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Cardiology, Aswan University, Cairo, Egypt
Dr. Amr Hanafy is currently working as a lecturer in Department of Cardiology in Aswan University, Cairo, Egypt. He has published numerous research papers and articles in reputed journals and has various other achievements in related studies. He has extended his valuable services towards the scientfic community with his extensive research work.
Research Article
Assessment of the Relationship between Galectine-3 and Cardiac Functions in Patients with Chronic Heart Failure
Author(s): Saud Mohamed Elsaughier*, Mohamed Kamal Salama, Amr Hanafy, Mahmoud M Ahmed and Ayman M Ibrahim
Background: HF biomarkers have growing importance in daily clinical practice as well as in clinical trials. Several biomarkers are used for diagnosis and prognosis of HF patients. Recently, Galectine-3 has been proposed for diagnosis and prognosis of HF. In this study we aimed to determine the relationship between galectine-3 level and cardiac functions in patients with chronic heart failure and its correlation with clinical manifestations. Methods: The current study enrolled 90 patients with chronic heart failure and then divided according to ejection fraction (EF) into two groups , group I included 60 patients with clinical manifestation of HF and EF <50%, group II included patients with clinical manifestation of HF and EF >50%.serum levels of Galectine-3 were measured in all patients with heart failure. Results: Level of galectine-3 was significantly increasing with advancing.. View More»
DOI:
10.35248/2167-0870.20.10.408