Clinical & Experimental Cardiology
Open Access

Department of Basic and Applied Medical Sciences, University of Ghent, Ghent, Belgium

Publications

• Mini Review   
  Exploring Cardiac Sympathetic Denervation as a Treatment Approach for Recurrent Ventricular Arrhythmias: A Concise Review
  Author(s): Andrei Gurau, Frank Bosmans, Andreas Barth, Malcolm V. Brock and Jinny S. Ha*
  
  Surgical Cardiac Sympathetic Denervation (CSD) has gained traction as a promising neuromodulatory therapy for Refractory Ventricular Tachyarrhythmias (RVT), particularly in patients with channelopathies and Ischemic (ICM) and Non-Ischemic Cardiomyopathies (NICM) who are refractory to conventional treatment. This mini review examines the pathophysiological role of the sympathetic nervous system in RVT and assesses the efficacy of Bilateral CSD (BCSD) through a literature review. Historical perspectives have traced the evolution of CSD from its initial use in intractable angina to its current application in ventricular arrhythmias. BCSD is associated with improved outcomes for refractory ventricular arrhythmias, with studies demonstrating approximately 60% reductions in implantable cardioverter defibrillator shocks and over 50% shock-and transplant-free survival at .. View More»
  DOI: 10.35248/2155-9880.24.15.874

  Abstract HTML PDF