ISSN: 2155-9570
Department of Health Sciences, Laboratory of Biochemistry, University of Milan, Milan, Italy
After receiving her PhD degree (2002) with a project on the role of peptidergic receptors and transporters of cerebellar neurotransmitters, as a post-doc fellow she studied the molecular and cellular effect of chronic hypoxia in both in vitro and in vivo model. She mainly focused on the mechanisms involved in cardiovascular damage and cardioprotection, investigating the balance between pro-survival and pro-apoptotic pathways.
Research
The Efficacy of a New lubricating Eyedrop in a Lipid Vehicle for the Treatment of Dry Eye Disease
Author(s): Chiara Quisisana, Luca Rossetti, Anna Caretti, Michele Dei Cas and Paolo Fogagnolo*
Aim: To evaluate the efficacy and safety of the new lipid tear substitute VisuEvo® in patients with dry eye disease (DED).
Methods: 19 patients with evaporative or iatrogenic DED were enrolled and evaluated at baseline, week 2 and week 6. After baseline, they were instructed to self-administer VisuEvo three times daily for the whole study duration. Tear break-Up Time (TBUT), Schirmer I, Ferning, osmolarity, cytokine and lipid expression, ocular surface staining, patient satisfaction, and OSDI score were measured.
Results: During the study, TBUT progressively increased from 3.0 ± 1.9 sec at baseline to 6.4 ± 1.7 sec at final visit (P<0.0001), and OSDI progressively decreased from 39 ± 12 at baseline to 20 ± 15 at final visit (P<0.0001). Osmolarity significantly reduced from 328 .. View More»
DOI:
10.35248/2155-9570.20.11.860