ISSN: 2161-0495
+44 1478 350008
Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Case Report
A Case of 40-Year Old Man with Organophosphate Poisoning that his Nicotinic Symptoms Responded Dramatically to Magnesium Sulphate
Author(s): Arman Hakemi*
Organophosphates are chemicals used in pesticides. These compounds are acetylcholinesterase inhibitors and prevent
the breakdown of acetylcholine. The accumulation of acetylcholine leads to the activation of muscarinic receptors
and the creation of cholinergic effects, including increased secretions. It also causes overstimulation of nicotinic
receptors, which can lead to respiratory arrest, which is the most common cause of death in organophosphate
poisoning. Drug treatment is with atropine and enzyme activator such as pralidoxime. In this study, we presented a
40-year-old man who presented to the emergency room due to suicide with organophosphate poisoning, who was
successfully treated with a combination of atropine and magnesium sulfate instead of pralidoxime... View More»
DOI:
10.35248/2161-0495.24.14.559