Journal of Antivirals & Antiretrovirals
Open Access

Egyptian Liver Research Institute and Hospital (ELRIAH), Faculty of Medicine, Sherbin, El Mansoura, Egypt

Biography

Ayman A Hassan works at Egyptian Liver Research Institute and Hospital (ELRIAH), Sherbin, El Mansoura, Egypt. The authors area research interests includes Infectious diseases, Virology, Medicine. He /she has authored of many research articles/books in the relevent areas.

Publications

• Research Article   
  Characterization of Hepatocellular Carcinoma Following Direct-Acting Antiviral Therapy: A Prospective Study
  Author(s): Gamal Shiha, Talal Amer, Nabiel NH Mikhail, Reham Soliman, Mohamed Elbasiony, Doaa Gad, Ayman A Hassan, Ali Bayoumi, Alaa Ibrahim and Mohammed Eslam
  
  Background and aim: Chronic Hepatitis C (CHC) remains the most common cause of Hepatocellular Carcinoma (HCC). Direct-Acting Antiviral (DAA) therapy reduce incident of HCC among HCV-infected patients, however the impact of these therapies on tumor behavior is less clear. Here, we compared the characteristics of HCC diagnosed before and after initiation of f DAA therapy in large population-based cohort. Patients and methods: In a prospective cohort of an outreached program in 73 villages across Egypt, 14,495 (91.2%) patients were treated with DAAs and followed after SVR for median of two years (12-45 months), Of those, 275 patients had HCC (166 patients before and 109 patients after the initiation of DAA therapy). Results: Patients who developed HCC after DAA had less tumor size, portal vein invasion, advanced stage accor.. View More»
  

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