Chemotherapy: Open Access
Open Access
ISSN: 2167-7700
ISSN: 2167-7700
Department of Pharmacy Practice, ISF College of Pharmacy, Punjab, India
Case Report
Oxaliplatin Triggered Hypersensitivity Reactions in Colorectal Cancer Patients: Case Report
Author(s): Ayushreeya Banga and Khadga Raj Aran*
Colorectal cancer stands as a significant global health concern, encompassing adenocarcinoma of both the colon and rectum. Recognized risk factors include advancing age and medical history of inflammatory bowel conditions like Crohn's disease or ulcerative colitis. Oxaliplatin, a platinum-based chemotherapy agent, serves as the frontline treatment for colorectal cancer due to its cytotoxic effects on cancerous cells. However, its use is not without complications, as hypersensitivity reactions can occur, posing challenges in patient management. This case report discusses two instances where patients undergoing chemotherapy for colorectal cancer developed grade two hypersensitivity reactions following oxaliplatin administration, the Naranjo probability scale was used to analyze the causation of the Adverse Drug Reactions (ADRs) and a score of 6 was obtained, indicating oxaliplatin as a .. View More»
DOI:
10.35248/2167-7700.24.12.218