Journal of Clinical Trials
Open Access

Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy

Publications

• Research Article   
  Effects of Hyaluronic Acid-Sorbitol Formulation in Patients Undergoing Knee Arthroscopy: A Randomized Controlled Single-Blind Clinical Trial
  Author(s): Simone Giusti*, B. Di Paola, Edoardo De Fenu, C. Caria and Ezio Adriani
  
  Background: Although there is no best irrigation solution for knee arthroscopy, many studies show that the most commonly irrigation fluids are toxic for the articular chondrocytes, suppressing their metabolism and function. The purpose of this study is to evaluate the clinical outcome of patients injected with 6 ml of hyaluronic acid (2%) and sorbitol (4%) formulation (Synolis VA) after knee arthroscopy and compare pain and functionality outcomes with patients who did not receive Synolis VA in the post-operative period. Materials and Methods: 60 patients were randomly divided using a computer-produced causal number generator algorithm into 2 groups. At the end of the procedure 30 patients received an intra-articular 6ml injection of Synolis VA the remaining 30 patients did not receive any treatment. Inclusion criteria: age 18 to 60 years, me.. View More»
  DOI: 10.35248/2167-0870.25.S32.004

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