ISSN: 2329-8901
Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas 77030, United States
was working as PhD scholar in the French National Institute for Agricultural Research loacted in France. Sophie Holowacz is the Editorial Board Member of many peer reviewed journals and area of expertise, as an Research Scholar credits with many publications in national and international journals. Sophie Holowacz is committed to highest standards of excellence and it proves through his/her co-authorship of many books.
Research
Human Breast Milk Promotes the Immunomodulatory Function of Probiotic Lactobacillus reuteri DSM 17938 in the Neonatal Rat Intestine
Author(s): Thomas K Hoang, Jasmin Freeborn, Ting Wang, Tu Mai, Baokun He, Sinyoung Park, Dat Q Tran, Stefan Roos, J Marc Rhoads and Yuying Liu*
Background and objective: Breast milk has many growth-promoting and immune-active components, including transforming growth factor-β, lactoferrin, lysozyme, immunoglobulin A, and prebiotics such as the human milk oligosaccharides. Treatment with Lactobacillus reuteri DSM 17938 (LR), a probiotic with immunomodulatory functions, significantly increases regulatory T cells (Tregs) in the intestinal mucosa of newborn suckling rats. In humans, treatment with LR of infants with colic reduces crying optimally if the infants are breast-fed. Therefore, we examined the effects of human breast milk (HBM) on LR-associated immune modulation.
Methods: Newborn rats were divided into 8 feeding groups, including dam-fed ± LR (106 CFU/kg bw/day, daily), formula-fed ± LR, formula with 20% (v/v) HBM-fed ± LR, and HBM.. View More»
DOI:
10.35248/2329-8901.19.7.210