Journal of Hematology & Thromboembolic Diseases
Open Access

Department of Paediatrics, Federal Medical Centre Bida, Niger, Nigeria

Publications

• Original Research Article   
  Newborn Screening for Haemoglobinopathies in Bida, North-Central Nigeria
  Author(s): Folayan OS*, Bello AO and Ernest SK
  
  Background: The global annual population of newborn with structural haemoglobin disorders is estimated at five million and Nigeria accounts for more than 30% of this with under-five mortality from haemoglobinopathies reaching 50%-90%. Despite this huge burden and a 15-fold reduction in deaths from haemoglobinopathies in countries that conduct newborn screening, most sub-Saharan Africa countries do not have a screening program. The widely used diagnostic haemoglobin electrophoresis is also not sensitive for newborn screening. Objectives: This study was carried out to determine haemoglobin phenotype patterns and frequency in neonates attending routine immunization clinics in Bida, and to identify factors associated with the occurrence of haemoglobinopathy. Materials and Methods: It was a descriptive cross-sectional s.. View More»
  DOI: 10.35248/2329-8790.23.11.537

  Abstract HTML PDF