Journal of Chromatography & Separation Techniques

Journal of Chromatography & Separation Techniques
Open Access

ISSN: 2157-7064

+44 1300 500008

Bing Yuan

Department of Bioseparation Engineering, University of Tokyo, Tokyo, Japan

Biography

Dr. Bing Yuan is a researcher in the Department of Bioseparation Engineering at the University of Tokyo, Japan. His work focuses on the development of advanced materials and techniques for bioseparation processes, particularly in the context of protein purification and analysis. Dr. Yuan has contributed to the field through his research on the synthesis and application of polyhedral silsesquioxane-based capillary monoliths in micro-Immobilized Metal Affinity Chromatography (μ-IMAC). This innovative approach aims to enhance the isolation and purification of histidine-tagged proteins, which are crucial in biochemical research and biotechnological applications. In his recent publication, "Advancing Protein Enrichment with Novel Polyhedral Silsesquioxane Capillary Monolith in μ-IMAC," Dr. Yuan details the synthesis and functionalization of these capillary monoliths. The study emphasizes the integration of polyhedral silsesquioxane into the polymer matrix via thiol-methacrylate polymerization, resulting in monoliths with enhanced mechanical stability, increased porosity, and expanded surface area. These improvements collectively enhance chromatographic performance, offering a promising tool for efficient protein purification. Dr. Yuan's research contributes significantly to the field of bioseparation engineering, particularly in the development of advanced materials for protein purification. His work holds promise for applications in proteomics research, biotechnology, and biomedical sciences, paving the way for improved protein purification methodologies and enhanced understanding of biological systems

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