Journal of Clinical & Experimental Dermatology Research
Open Access

Department of Dermatology, University Hospital La Fe, Valencia, Spain

Biography

Blanca de Unamuno Bustos is from Spain who belongs to the Department of Dermatology, University Hospital La Fe, Valencia, Spain. Dr. has a special interest in Dermatology, Psoriasis, Acne, Skin, Actinic keratosis.

Publications

• Research Article   
  Long-Term Efficacy of a New Medical Device Containing Fernblock^® and DNA Repair Enzyme Complex in the Treatment and Prevention of Cancerization Field in Patients with Actinic Keratosis
  Author(s): Blanca de Unamuno Bustos*, Natalia Chaparró Aguilera, Inmaculada Azorín García, Anaid Calle Andrino, Margarita Llavador Ros, Regina Rodrigo, María Vitale, Salvador González and Rafael Botella
  
  Introduction: Actinic keratosis (AKs) are part of the cancerization field, a region adjacent to AKs containing subclinical and histologically abnormal epidermal tissue due to Ultraviolet (UV)-induced DNA damage. The photoproducts, “as consequence of DNA damage induced by UV”, are mainly cyclobutane pyrimidine dimers (CPDs). Fernblock® demonstrated in previous studies significant reduction of the number of CPDs induced by UV radiation. Photolyases are a specific group of enzymes that remove the major UV-induced DNA lesions by a mechanism called photo-reactivation. Methods: A monocentric, prospective, controlled, and double blind interventional study was performed to evaluate the effect of a new medical device (NMD) containing a DNA-repair enzyme complex (photolyases, endonucleases and glycosilases), a combination of.. View More»
  DOI: 10.35248/2155-9554.19.10.499

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