Journal of Clinical Toxicology
Open Access

Department of Biomedicine, Jeonbuk National University, Jeonju, South Korea

Publications

• Case Report   
  Serial EEG changes in Low-Dose Baclofen Intoxication
  Author(s): Han Uk Ryu*, Hong Jin Kim, Hyun Goo Kang and Byoung Soo Shin
  
  Baclofen, a derivative of the neurotransmitter γ-aminobutyric acid, is widely used to treat adjuvant pain and skeletal muscle spasms. Common side effects of baclofen can cause dizziness, drowsiness, or weakness, in addition to serious central nervous system problems such as loss of brain stem reflex, comatose mentality, myoclonic jerk, and seizures. Several cases have reported that baclofen intoxication is provoked by high overdose ingestion in a short period. We report two cases of serial EEG changes in low-dose baclofen intoxication that showed burst and suppression patterns and eventually returned to normal EEG in correlation with clinical improvement... View More»
  DOI: 10.35248/2161-0495.23.13.536

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