ISSN: 2155-9554
+44 1478 350008
Department of Dermatology, Medical University of Warsaw, Koszykowa, Warsaw, Poland
C Kowalewski is from poland who belongs to the Department of Dermatology, Medical University of Warsaw, Koszykowa, Warsaw, Poland. Dr. has a special interest in Dermatology, Skin, Laser scanning.
Research Article
Laser Scanning Confocal Microscopy for Diagnostics of Brunsting-Perry Type Cicatrical Pemphigoid Cases, along with Review of Literature
Author(s): K Osipowicz*, B Jakubowska, C Kowalewski, T Hashimoto and K Wozniak
Background: In the literature there are a few reported cases of cicatrical pemphigoid Brunsting-Perry type (CPBP). CPBP is well clinically characterized by clinical research, however is heterogeneous in a term of immunological findings. Laser scanning confocal microscopy (LSCM) is a helpful tool for diagnostics of cicatricial pemphigoid in general, especially when circulating antibodies are not detectable.
Objectives: Application of LSCM for the first time in a case with clinical features of CPBP and review the literature.
Methods: Skin biopsy was taken for LSCM studies. LSCM technique relies on comparison between the location of IgG/IgA deposits and basement membrane zone (BMZ) markers: antibodies directed to laminin 332 served as a marker of lower part of lamina lucida, whereas antibodies to type IV collagen served as .. View More»