ISSN: 2167-0412
+44 1300 500008
Department of Chemistry, Federal Institute of Education, Science and Technology of Maranhão, Campus São LuÃs- Monte Castelo, Maranhão, 65030-005, Brazil
Research Article
Luehea candicans Increase In Vitro Cell Cancer Metabolism Even with High Polyphenols Content
Author(s): Camara MBP, Rabelo ACS*, Borghesi J, Bessa F, da Silva Nunes Barreto R, Angélica Miglino M, Costa Carneiro FJ and Cantanhede Filho AJ
Brazil is the country with the greatest biodiversity; however, most of the plants are used empirically, without scientific evidence. Luehea candicans, popularly called as-açoita-cavalo, is a specie characteristic of the Brazilian Cerrado Biome, used for fight hemorrhages, dysenteries, diarrhea, rheumatism and tumors. On the other hands, there are practically no studies about chemical composition and assess of their biological effects. Thus, the aim of this investigation was characterize and evaluate the antitumor potential of crude hydroethanolic extract from the bare stem parts of this plant, as well as its ethyl acetate and methanolic fractions. For the characterization, the crude extract was submitted to qualitative (phytochemical screening and analysis by direct flow injection by mass spectrometry-FIA-ESI-IT-MS) and quantitative tests (determination of phenolic com.. View More»
DOI:
10.35248/2167-0412.19.8.329