Lupus: Open Access
Open Access
ISSN: 2684-1630
+44 1300 500008
ISSN: 2684-1630
+44 1300 500008
Division of Rheumatology, IRCCS Foundation Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
He belongs from Division of Rheumatology, IRCCS Foundation Policlinico San Matteo in University of Pavia, 27100 Pavia at Italy. His Subjects of Specialization are Rheumatology, Gynecology, Health , Innate Immunity, life biology.
Research
Effect of Known and Previously Undiagnosed Undifferentiated Connective Tissue Diseases on Pregnancy Outcome
Author(s): Fausta B, Elena L*, Chiara C, Véronique R, Camilla B, Irene DM, Beatrice R, Carlomaurizio M and Arsenio S
Objective: Previously undiagnosed and known UCTDs are associated with severe obstetric and perinatal outcomes compared to controls.
Methods: Previously undiagnosed UCTDs and controls were screened using a two-step approach (selfadministered questionnaire and test for rheumatic autoantibodies) and evaluation by a rheumatologist. Pregnant subjects with known UCTD were recruited at the first trimester of pregnancy during their rheumatologic follow-up. Pregnancy complications such as preeclampsia, fetal growth restriction, small for gestational age, umbilical artery PI>95th percentile, prematurity<37 weeks ’gestation, were evaluated in cases and controls.
Results: Out of the 5199 women screened, 114 (2.2%) had a previously undiagnosed UCTD and 65 (1.25%) were diagnosed with major connective tissue diseases. Wom.. View More»