Reproductive System & Sexual Disorders: Current Research
Open Access
ISSN: 2161-038X
+44 1300 500008
ISSN: 2161-038X
+44 1300 500008
Department of Obstetrics and Gynecology, The University of Medicine and Pharmacy Iuliu Hatieganu, 400012 Cluj-Napoca, Romania
Research Article
The Distance between the Embryo and the Yolk Sac in Correlation to the Serum Level of Placental Growth Factor: How Reliable is it?
Author(s): Carmen Elena Bucuri, Razvan Ciortea*, Valentin Aron Constantin Oprea, Andrei Mihai Malutan, Renata Nicula, Mihaela Daniela Oancea, Maria Patricia Rada and Dan Mihu
Background: The etiology of embryonic demise is multifactorial, with chromosomal abnormalities being the most common (60%). The purpose of this study is to evaluate the correlation between a serum biomarker, Placental Growth Factor (PlGF) and an ultrasonographic parameter, the distance between Yolk Sac (YS) and embryo (DYSE), in assessing the prognosis of first trimester pregnancies outcome.
Materials and findings: The study is a case-control prospective analysis that includes two groups of patients: 81 patients with viable first-trimester pregnancy and 89 patients with embryonic demise, all of the patients having amenorrhea between 6 and 11 weeks. The endovaginal ultrasonographic exploration was performed to evaluate the distance between the lower pole of the embryo and the yolk sac. From each subject enrolled in the study, 20 ml of blood w.. View More»
DOI:
10.35248/2161-038X.22.11.311