Journal of Probiotics & Health
Open Access
ISSN: 2329-8901
ISSN: 2329-8901
Biochemistry Department, Havana University, La Habana, Cuba
Research
Randomized Clinical Trials Demonstrate the Safety Assessment of Dietzia natronolimnaea C79793-74 for Use as a Probiotic in Humans
Author(s): Gissel García*, Josanne Soto, Jesus Barreto, Angela Gutiérrez, Carmen Soto, Ana Beatriz Pérez, Judith Peña and Raúl J. Cano*
Dietzia natronolimnaea C79793-74 have been identified as of potential probiotic strain for the management of
Crohn's disease in humans. The following research presents a series of studies that establish the safety profile of this
strain for use as a probiotic supplement. The genotypic characterization of Dietzia natronolimnaea C79793-74 was
conducted through a combination of 16S rRNA analysis and genomic sequencing and the analysis was conducted
using MiGA and MyTaxa. The safety study also involved a search of the assembled genome for the presence of
antibiotic resistance genes and virulence factors using the Curated Database of Antibiotic Resistance genes (CARD)
and Virulence Factor Database (VFDB) databases, respectively. Notably, Dietzia natronolimnaea C79793-74 exhibited
no evidence of antibiotic resistance or virulence factors in th.. View More»
DOI:
10.35248/2329-8901.23.11.336