Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Department of Anesthesiology, Universidad Nacional Autónoma De Mexico City, Mexico
Research Article
Transoperative Management of Cerebral Edema Secondary to Supratentorial Tumors; Hypertonic Saline 3% vs. Mannitol: A Reconstruction of a Cohort
Author(s): González-Chávez María del Soc*, Jiménez-Aguilar Rosalinda, Carmona-Suazo José Antonio, Torres- Salazar Quitzia Libertad, Holguín-Gutiérrez Aldo Uriel, Ramírez-Aguilar Ricardo, García-Elías Omar Saúl, Ledezma-González Elena and Arcos-Soto Sebastián
Introduction: During a craniotomy, the intracranial pressure value is reduced; however, the opening of the
compartment may generate transcalvarial herniation with risk of secondary injury by venous compression over the
edge of the craniotomy. Cerebral relaxation has been considered an important neuroprotective measure. Historically,
cerebral edema has been managed with mannitol; nevertheless, the use of 3% Hypertonic Saline (HS) as first choice
therapy is increasing.
Material and methods: Cohort, observational, retrospective, analytical, longitudinal study with a control group.
Thirty ASA II-III patient files were included, aged 18 to 60 years, with a diagnosis of supratentorial brain tumor,
serum sodium between 135 and 155 mEq/L and clinical intracranial hypertension. The groups were constituted
considering the management.. View More»
DOI:
10.35248/2155-6148.23.14.1098