ISSN: 2472-1077
+44 1478 350008
Institute of Mental Health, Buangkok Green Medical Park, Singapore
Chan Christopher Yi Wen affiliated with Institute of Mental Health, Buangkok Green Medical Park, Singapore. Has 8 research publications on online global platforms. Skills and Expertise lies in the fields of Pharmacogenomics, Psychiatry, Schizophrenia
Case Report
Case Report: Sodium Valproate-Induced Neutropenia in a Patient with Bipolar Disorder
Author(s): Rajagopalan Arvind*, Lim Shuli, Chan Christopher Yi Wen, Mok Yee Ming and Chandwani Nisha
Background: There are sporadic case-reports suggesting an association between sodium valproate and neutropenia, though the majority of these are in cases of paediatrics and epilepsy. There are a few cases of psychiatric patients developing neutropenia after newly being started on sodium valproate. We present a patient, previously on long-term sodium valproate therapy, who developed neutropenia after being restarted on sodium valproate.
Case report: A 52-year-old Chinese man with bipolar disorder, previous well on a combination of sodium valproate and risperidone, was re-admitted for a manic relapse after a period of non-compliance. He developed neutropenia that coincided with increases in sodium valproate dose, and only resolved upon discontinuation of sodium valproate, despite continued increases in risperidone dose. Other investigations fo.. View More»
DOI:
10.35248/2472-1077.22.8.166