ISSN: 2472-1077
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Institute of Mental Health, Buangkok Green Medical Park, Singapore
Chandwani Nisha is affiliated with Institute of Mental Health, Buangkok Green Medical Park, Singapore. Skills and Expertise lies in the fields of Lipid metabolism. Pharmacogenomics, Psychiatry, Schizophrenia, Neuropsychiatry, Biological Psychiatry, Clinical Psychiatry, Psychopathology, Psychopharmacology
Case Report
Case Report: Sodium Valproate-Induced Neutropenia in a Patient with Bipolar Disorder
Author(s): Rajagopalan Arvind*, Lim Shuli, Chan Christopher Yi Wen, Mok Yee Ming and Chandwani Nisha
Background: There are sporadic case-reports suggesting an association between sodium valproate and neutropenia, though the majority of these are in cases of paediatrics and epilepsy. There are a few cases of psychiatric patients developing neutropenia after newly being started on sodium valproate. We present a patient, previously on long-term sodium valproate therapy, who developed neutropenia after being restarted on sodium valproate.
Case report: A 52-year-old Chinese man with bipolar disorder, previous well on a combination of sodium valproate and risperidone, was re-admitted for a manic relapse after a period of non-compliance. He developed neutropenia that coincided with increases in sodium valproate dose, and only resolved upon discontinuation of sodium valproate, despite continued increases in risperidone dose. Other investigations fo.. View More»
DOI:
10.35248/2472-1077.22.8.166