ISSN: 2161-0517
Department of Biomedical Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya
Research Article
Pneumocystis jirovecii in TB: Smear-Negative and Retreatment Cases at the Coast General Hospital
Author(s): Saitoti A*, Wamunyokoli F, Njerwanna SL and Christine Bii
The opportunistic fungus Pneumocystis jirovecii causes PneumocystisPneumonia (PCP), a life-threatening infection in HIV/AIDS and other immunocompromised patients. The seemingly low prevalence of P. jirovecii pneumonia in sub-Saharan Africa has been a matter of great debate; unsuitable diagnostic practices have been added to the uncertainty of PCP prevalence. Few studies have evaluated the utility of easily obtainable samples such as expectorated sputum for diagnosis. Smear -ve pulmonary TB is diagnosed according to clinical and radiographic criteria, due to unavailability of mycobacterial cultures. In high seroprevalence areas of HIV/AIDS there’s a concern that other opportunistic infections apart from TB, such as P. jirovecii may be missed. We proposed to determine the prevalence of P. jirovecii in confirmed TB smear negative and retreatment .. View More»
DOI:
10.35248/2161-0517.22.11.246