Journal of Clinical & Experimental Dermatology Research
Open Access

University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam

Biography

Chuyen Thi Hong Nguyen is from Vietnam who belongs to the University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam. Dr. has a special interest in Dermatology, Drug adverse reaction, Skin, Psoriasis, Acne.

Publications

• Case Report   
  Hypereosinophilia as a Rare Side Effect of Methotrexate in a Patient with Erythrodermic Psoriasis: The First Case Report
  Author(s): Thanh Thai Van Le, Chuyen Thi Hong Nguyen*, Hao Trong Nguyen, Chau Van Tro, Giang Huong Tran, Lien Thi Bich Nguyen and Trung The Van
  
  Methotrexate (MTX) has been approved for the treatment of psoriasis and is considered to be effective and relatively safe. This drug was widely used for treatment of psoriasis in Vietnam for many years. Life-threatening MTX toxicity is rare but may rapidly develop when the drug is administered. In line with the interface dermatitis and a remarked eosinophilic infiltration in the cutaneous lesion, the diagnosis of hypereosinophilia as an adverse reaction in our patient was supported by the dramatic improvement of symptoms and decreased eosinophils after withdrawal of MTX. To the best of our knowledge, this is the first case that showed isolated hypereosinophilia as an adverse reaction of MTX in psoriasis treatment that may challenge in early recognition. Awareness and prompt recognition of this severe adverse reaction can result in life-saving discontinuation of MTX... View More»
  DOI: 10.35248/2155-9554.19.10.501

  Abstract HTML PDF